Lesi sizindalwazi sisetshenziswa ibhizinisi noma amabhizinisi aphethwe yi-Informa PLC futhi wonke amalungelo okukopisha ahlala kubo.Ihhovisi elibhalisiwe le-Informa PLC yi-5 Howick Place, e-London SW1P 1WG.Ibhaliswe eNgilandi naseWales.Inombolo yepholisi: 8860726.
Ithimba lomcwaningi we-Cal Tech eliholwa u-Wei Gao, uprofesa wobunjiniyela bezinto eziphilayo, lithuthukise inzwa egqokekayo eqapha amazinga ama-metabolites nemisoco egazini lomuntu ngokuhlaziya umjuluko wabo.Izinzwa zomjuluko zangaphambilini beziqondise kakhulu izinhlanganisela ezivela ekugxilweni okuphezulu, njengama-electrolyte, i-glucose, ne-lactate.Le entsha izwela kakhulu futhi ithola izingxube zokujuluka ezindaweni eziphansi kakhulu.Kulula futhi ukuwenza futhi kungakhiqizwa ngobuningi.
Umgomo wethimba inzwa evumela odokotela ukuthi baqhubeke beqapha isimo seziguli ezinezifo ezifana nesifo senhliziyo nemithambo yegazi, isifo sikashukela, nesifo sezinso, konke okubeka amazinga angavamile ezakhi noma ama-metabolite egazini.Iziguli beziyoba ngcono uma udokotela wazo azi okwengeziwe ngezimo zazo zomuntu siqu futhi le ndlela igwema ukuhlolwa okudinga izinaliti nokuthathwa kwesampula yegazi.
“Lezo zinzwa zokujuluka ezigqokekayo zingathwebula ngokushesha, ngokuqhubekayo, futhi ngokunganaki izinguquko empilweni emazingeni amangqamuzana,†kusho uGao.“Bangenza ukuqapha komuntu siqu, ukuxilonga kusenesikhathi, kanye nokungenelela okufika ngesikhathi kwenzeke.â
Inzwa incike kuma-microfluidics alawula amanani amancane oketshezi, ngokuvamile ngamashaneli angaphansi kwekota yemilimitha ububanzi.Ama-Microfluidics afaneleka kahle ohlelweni ngoba anciphisa umthelela wokuhwamuka komjuluko kanye nokungcoliswa kwesikhumba ekunembeni kwenzwa.Njengoba umjuluko osanda kunikezwa ugeleza kuma-microchannels wenzwa, ukala ngokunembile ukwakheka komjuluko futhi uthwebula izinguquko ekugxilweni kwawo ngokuhamba kwesikhathi.
Kuze kube manje, uGao nozakwabo bathi, izinzwa ezigqokekayo ezisekelwe ku-microfluidic zakhiwe kakhulu ngendlela ye-lithography-evaporation, edinga izinqubo zokwenziwa eziyinkimbinkimbi nezimba eqolo.Ithimba lakhe likhethe ukwenza ama-biosensor alo nge-graphene, uhlobo lwekhabhoni olufana neshidi.Kokubili izinzwa ezisekelwe ku-graphene kanye namashaneli e-microfluidics adalwe ngokuqopha amashidi epulasitiki ngelaser ye-carbon dioxide, idivayisi evame kakhulu ukuthi itholakale kubathandi basekhaya.
Ithimba locwaningo liklame inzwa yalo ukuthi liphinde lilinganise izinga lokuphefumula nenhliziyo, ngaphezu kwamazinga e-uric acid ne-tyrosine.I-Tyrosine yakhethwa ngoba ingaba inkomba yokuphazamiseka kwe-metabolic, isifo sesibindi, ukuphazamiseka kokudla, nezimo ze-neuropsychiatric.I-Uric acid yakhethwa ngenxa yokuthi, emazingeni aphakeme, ihlotshaniswa ne-gout, isimo esibuhlungu samalunga esikhula emhlabeni wonke.I-Gout yenzeka lapho amazinga aphezulu e-uric acid emzimbeni eqala ukucwebezela emalungeni, ikakhulukazi lawo ezinyawo, okubangela ukucasuka nokuvuvukala.
Ukubona ukuthi izinzwa zisebenze kahle kangakanani, abacwaningi bakuhlole kubantu abanempilo kanye neziguli.Ukuze bahlole amazinga e-sweat tyrosine athonywa ukuqina komzimba womuntu, basebenzise amaqembu amabili abantu: abasubathi abaqeqeshiwe kanye nabantu abanokufaneleka okulinganiselwe.Njengoba bekulindelekile, izinzwa zibonise amazinga aphansi e-tyrosine kumjuluko wabasubathi.Ukuhlola amazinga e-uric acid, abacwaningi baqaphe umjuluko weqembu labantu abanempilo ebelizila ukudla, futhi nangemva kokuba abafundi bedle ukudla okunothe ngama-purines—izinhlanganisela zokudla ezigaywe zibe i-uric acid.Inzwa yabonisa amazinga e-uric acid akhuphuka ngemva kokudla.Ithimba le-Gao lenze ukuhlolwa okufanayo neziguli ze-gout.Inzwa yabonisa ukuthi amazinga e-uric acid ayephezulu kakhulu kunawabantu abanempilo.
Ukuhlola ukunemba kwezinzwa, abacwaningi badonsa futhi bahlola amasampula egazi ezigulini ze-gout kanye nezifundo ezinempilo.Izilinganiso zezinzwa zamazinga e-uric acid zihlobene kakhulu namazinga ayo egazini lazo.
UGao uthi ukuzwela okukhulu kwezinzwa, kanye nendlela ezingenziwa kalula ngayo, kusho ukuthi ekugcineni zingase zisetshenziswe iziguli emakhaya ukuqapha izimo ezifana ne-gout, isifo sikashukela, kanye nezifo zenhliziyo.Ukuba nolwazi olunembile lwesikhathi sangempela mayelana nempilo yazo kungase kuvumele iziguli zilungise amazinga azo emithi nokudla njengoba kudingeka.
Isikhathi sokuthumela: Dec-12-2019